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ys 49  (MedChemExpress)


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    MedChemExpress ys 49
    Ys 49, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 22 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ys 49/product/MedChemExpress
    Average 94 stars, based on 22 article reviews
    ys 49 - by Bioz Stars, 2026-02
    94/100 stars

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    ACZF improves colitis via pathways involving PI3K/AKT signaling. (a) Representative immunoblots and the relative expression levels of AKT, p-AKT, PI3K, and p-PI3K in colon tissues from different treatment groups; (b) ZO-1and claudin-1 expression in the colon tissues of the colitis mice was detected by Western blot; (c) Colonic cytokine levels of TNF-α, IL-1β, IL-6, and IL-10. Data represent means ± SD (n = 4). **p < 0.01 vs. Control group; ##p < 0.01 vs. Model group; $ p < 0.05 vs. ACZF group; $$ p < 0.01 vs. ACZF group.

    Journal: Frontiers in Pharmacology

    Article Title: Molecular mechanisms of the anchang group prescription in treating radiation enteritis: network pharmacology analysis and experimental evidence

    doi: 10.3389/fphar.2025.1524925

    Figure Lengend Snippet: ACZF improves colitis via pathways involving PI3K/AKT signaling. (a) Representative immunoblots and the relative expression levels of AKT, p-AKT, PI3K, and p-PI3K in colon tissues from different treatment groups; (b) ZO-1and claudin-1 expression in the colon tissues of the colitis mice was detected by Western blot; (c) Colonic cytokine levels of TNF-α, IL-1β, IL-6, and IL-10. Data represent means ± SD (n = 4). **p < 0.01 vs. Control group; ##p < 0.01 vs. Model group; $ p < 0.05 vs. ACZF group; $$ p < 0.01 vs. ACZF group.

    Article Snippet: The PI3K activator YS-49 (No. HY-15477) was obtained from MedChem Express.

    Techniques: Western Blot, Expressing, Control

    A model illustration of ACZF inhibits PI3K/AKT pathway, alleviates radiation-induced intestinal epithelial dysfunction and intestinal inflammation.

    Journal: Frontiers in Pharmacology

    Article Title: Molecular mechanisms of the anchang group prescription in treating radiation enteritis: network pharmacology analysis and experimental evidence

    doi: 10.3389/fphar.2025.1524925

    Figure Lengend Snippet: A model illustration of ACZF inhibits PI3K/AKT pathway, alleviates radiation-induced intestinal epithelial dysfunction and intestinal inflammation.

    Article Snippet: The PI3K activator YS-49 (No. HY-15477) was obtained from MedChem Express.

    Techniques: